Work

Paracoccidioidomycosis as a Manifestation of Immune Reconstitution Inflammatory Syndrome in an HIV Patient: An Uncommon Presentation

Year: 2025

Type: article

Abstract: A 50-year-old HIV-positive woman, nonadherent to antiretroviral therapy, developed asthenia, weight loss, and lymphadenopathy after restarting treatment. Imaging revealed adenopathies and a breast nodule, with biopsies confirming Paracoccidioides brasiliensis. Despite initial therapy failure (trimethoprim-sulfamethoxazole), liposomal amphotericin, corticosteroids, and a regimen change led to partial improvement until a psoas abscess required drainage, ultimately stabilizing her condition.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofaf141