Community and hospital-based laboratory surveillance for influenza, RSV, and SARS-CoV-2 during the 2023-2024 season, Lyon, France
Year: 2025
Type: preprint
Study design: Observational Study
Abstract: Influenza, respiratory syncytial virus (RSV) and SARS-CoV-2 are among the main viruses circulating in the population, with a significant burden on public health. While individuals at higher risk are more likely to develop severe symptoms leading to hospitalization, viral circulation in the community remains less extensively monitored. This study compared viral circulation between RELAB, a recently established community-based laboratory surveillance network (n=22,843 tested patients) and hospital surveillance at the Hospices Civils de Lyon, France (n=23,046 tested patients), for the season 2023-2024. For influenza and SARS-CoV-2, similar trends were observed in at-risk populations (children under five years and adults over 65 years) in both settings. Circulation of these two viruses was first detected in the community and insights from the young adult population (19-64 years) were only captured in the community network. Circulation of RSV was more intense in terms of number of cases and started in the pediatric population, which was more represented in the hospital. In conclusion, this study highlighted the complementarity between community and hospital surveillance, as different populations and periods of viral circulation were observed.
Authors: Cécile Chauvel, Jean-Sébastien Casalegno, Benoit VISSEAUX, Vincent Vieillefond, Stéphanie Haim-Boukozba, Vincent Enouf, Emmanuel Chanard, Margaux Fabre, Marie-Anne Rameix Welti, Antoine Oblette, Jean-Marc Giannoli, Juliette Paireau, Laurence Josset, Bruno Lina, Alexandre Gaymard, Simon Cauchemez, Florence Morfin, Marta Nunes C, Antonin Bal
Institutions: Hospices Civils de Lyon, Institut Pasteur, Université Paris Cité
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4408259746