Work

A novel molecularly imprinted polymers on self-assembly monolayer gold electrode impedimetric detection of dopamine

Year: 2025

Type: article

Abstract: Dopamine (DA), a neurotransmitter of the catecholamine class that has a range of functions in the mammalian central nervous system, is used to diagnose neurodegenerative diseases like schizophrenia, Parkinson’s illness, and Alzheimer’s disease. Therefore, it is an important biomarker to assess these diseases by measuring with low-cost, sensitive, and selective methods. In this research, we provided these advantages by engineering a molecularly imprinted impedimetric sensor to detect dopamine. The surface was modified with boronic acid residues and aminophenylboronic (APBA) acid and pyrrole-3-carboxylic (PyCOOH) acid were used as functional monomers around dopamine. Detection of dopamine was carried out by electrochemical impedance spectroscopy (EIS). According to the calibration curve between 100 and 600 pM (R 2 = 0.9517), the sensor system’s performance parameters were established, and the limit of detection (LOD) and limit of quantification (LOQ) were discovered to be 30.34 and 95.82 pM, respectivey.

Source: Journal of Materials Science Materials in Electronics

DOI: 10.1007/s10854-025-14375-0

Authors: Hilmiye Deniz Ertuğrul Uygun, M. Nalan Demir

Institution: Dokuz Eylül University

Language: English

Topic: Electrochemical sensors and biosensors

Subfield: Electrical and Electronic Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,990