Work

Nanourchin‐like Uricase‐Poly( L ‐proline) Conjugate with Retained Enzymatic Activity, Mitigated Immunogenicity, and Sustained Efficacy Upon Repeated Administrations

Year: 2025

Type: article

Source: Angewandte Chemie

DOI: 10.1002/ange.202425559

Authors: Ruichi Zhao, Yangming Zhang, Banlai Ruan, Hairuo Zhang, Niannian Lv, Jiayi Li, Yuhe R. Yang, Xiaozhou Luo, Hua Lu

Institutions: Peking University, Beijing National Laboratory for Molecular Sciences, Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen Institute of Synthetic Biology, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Shenzhen Scientific and Technological Foundation, Beijing Municipal Natural Science Foundation, Key Technologies Research and Development Program, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences

Awards: G1155197308, 面向淋巴瘤治疗的蛋白降解靶向嵌合体（PROTAC）纳米递送系统, G6069521603, G6618993327, G7355502002, G7798664887

OpenAlex ID: W4408267522

FWCI: 1.015

Cites: 64

Cited by: 4

Related to: 10