Work

Managing elderly patients with dual metastatic cancers—navigating diagnostic and treatment challenges

Year: 2025

Type: article

Abstract: Prostate and colorectal adenocarcinoma are among the most common primary cancer diagnoses in the United States, with 29% of new cancer diagnoses among adult men in 2024 expected to arise from the prostate and another 15% across men and women being colorectal in origin. Given therapeutic advancements leading to improved survival, individuals with prostate cancer have the highest estimated probability of concurrent secondary primary malignancy. This represents a clinical dilemma as the treatment for each is distinct and impacted by histology, stage, and molecular findings. Herein, we describe a patient with significant comorbidities, found to have simultaneous metastatic prostate and colorectal adenocarcinomas, who achieved sustained complete remission of liver and lung metastases with a chemohormonal regimen.

Source: The Oncologist

DOI: 10.1093/oncolo/oyaf026

Authors: Zane Gray, Nicholas Levonyak, Liwei Jia, Richard Ahn, Jyoti Balani, Jue Wang

Institution: The University of Texas Southwestern Medical Center

Language: English

Topic: Multiple and Secondary Primary Cancers

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,852