Work

Single‐Benzene‐Based Clickable Fluorophores for In Vitro and In Vivo Bioimaging

Year: 2025
Type: article
Abstract: A series of miniaturized, clickable single-benzene-based fluorophores derived from tetrafluoroterephthalonitrile is reported. Fluorophores based on a tetrahydroquinoxaline skeleton exhibited improved photophysical properties due to enhanced electron delocalization between donor and acceptor groups compared to those with a dihydro[1,4]thiazine skeleton. These easily synthesized clickable fluorophores were successfully applied in both in vitro and in vivo bioimaging following protein conjugation.
Language: English
Open Access status: hybrid
Estimated APC paid: $3,880
OpenAlex ID: W4408308500
FWCI: 0.845
Cites: 43
Cited by: 6
Related to: 10