Light‐Driven Structural Detachment and Controlled Release in Smart Antibacterial Multilayer Platforms
Year: 2025
Type: article
Abstract: Smart materials, especially light‐responsive, have become a key research area due to their tunable properties. It is related to the ability to undergo physical or chemical changes in response to external stimuli. Among them, photothermal responsive materials have attracted great interest. This study focuses on the development of a multilayer system (MS) consisting of benzophenone‐modified polydimethylsiloxane (PDMS) ring and a thermo‐responsive core made of poly(N‐isopropylacrylamide‐co‐N‐isopropylomethacrylamide) (P(NIPAAm‐co‐NIPMAAm)), gelatin, and gelatin methacrylate (GelMA). The system utilizes the thermal sensitivity of P(NIPAAm‐co‐NIPMAAm) and the photothermal effect of gold nanorods (AuNRs) to achieve an on‐demand controlled release mechanism within 6 min of near‐infrared (NIR) light irradiation. The mechanical properties investigated in the compression test show significant improvement in MS, reaching 60 times greater value than the material without a PDMS ring. In addition, NIR irradiation for 15 min activated the antimicrobial properties, eliminating 99.9% of E. Coli and 100% of S. Aureus, thus presenting pathogen eradication. This platform provides a versatile methodology for developing next‐generation smart materials, advanced delivery mechanisms, and multifunctional nanostructured composites. This work highlights the potential of photosensitive materials to revolutionize the field of soft robotics, optics and actuators, and on‐demand systems by providing precise control over release dynamics and improved material properties.
Language: English
Subfield: Mechanical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,150
Funder: Narodowym Centrum Nauki
Award: G6286547082
OpenAlex ID: W4408310780