Work

To Establish the Relationship between Proton Pump Inhibitors (PPIS) and Acute Interstitial Nephritis (AIN). Study Protocol

Year: 2025

Type: article

Abstract: In India, utilization of PPI varies from 45 to 85%. PPIs were used in 82.96% of patients with chronic kidney disease. However, nowadays several case reports are suggesting PPI that induces AIN. The exact rate of this rare adverse event is difficult to estimate because many patients are taking multiple medications, which also make it difficult to establish a causal relation between AIN and PPI. Early detection of AIN and immediate discontinuation of the culprit drug may prevent the progress of AIN to the end stage of chronic kidney disease. So we planned a study to establish the relationship between PPI and AIN, if any.

Source: Journal of Pharmacy And Bioallied Sciences

DOI: 10.4103/jpbs.jpbs_1966_24

Authors: Bite Bapurao, Swanand Pathak, Ranjit Sidram Ambad

Institution: Datta Meghe Institute of Higher Education and Research

Language: English

Topic: Acute Kidney Injury Research

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $250