Work

Twists, turns and jumps: T6SS evolution within species

Year: 2025

Type: article

Abstract: The type VI secretion system mediates interbacterial antagonism between Gram-negative bacteria through delivery of toxic effector proteins. A recent comprehensive genomic analysis by Habich et al. reveals interesting features of the evolution of T6SSs and their corresponding effectors in Pseudomonas aeruginosa, raising questions about functional specialization of the system.

Source: Trends in Microbiology

DOI: 10.1016/j.tim.2025.02.015

Authors: Beth A. Shen, S. Brook Peterson, Joseph D. Mougous

Institutions: University of Washington, Howard Hughes Medical Institute

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $7,030

Funders: Howard Hughes Medical Institute, University of Washington, National Institutes of Health, Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases