Work

Immune molecule links COVID‑19 with severe inflammatory disorder in children

Year: 2025

Type: article

Abstract: The immune molecule TGFβ has been found to weaken immune defences against latent viruses, triggering reactivation of the Epstein–Barr virus. This mechanism links TGFβ release in SARS-CoV-2 infection to multisystem inflammatory syndrome in children, and could inform the development of therapies for managing this serious condition. The molecule TGFβ suppresses the ability of T cells to protect against latent Epstein–Barr virus.

Source: Nature

DOI: 10.1038/d41586-025-00735-7

Language: English

Topic: Kawasaki Disease and Coronary Complications

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $12,690

OpenAlex ID: W4408345156

FWCI:

Cites: 5

Cited by:

Related to: 10