Work

Integrative whole slide image and spatial transcriptomics analysis with QuST and QuPath

Year: 2025

Type: article

Abstract: The integration of AI in digital pathology, particularly in whole slide image (WSI) and spatial transcriptomics (ST) analysis, holds immense potential for enhancing disease understanding. Despite challenges such as training pattern preparation and resolution disparities, the convergence of these technologies can unlock insights. We introduce QuST, a QuPath extension that bridges the gap between WSI and ST at single-cell level, highlighting the power of this integrated approach in disease biology.

Source: npj Precision Oncology

DOI: 10.1038/s41698-025-00841-9

Authors: Chao-Hui Huang, Sara Lichtarge, Diane Fernandez

Institution: Pfizer (United States)

Language: English

Topic: AI in cancer detection

Subfield: Artificial Intelligence

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,090