Sodium channel blockers for the treatment of focal epilepsy: A Chinese expert consensus
Year: 2025
Type: article
Abstract: PURPOSE: To provide consensus-based recommendations for the use of sodium channel blockers (SCBs) in the management of focal epilepsy. METHODS: A three-round modified Delphi procedure was conducted among a Delphi panel of 24 Chinese experts to build a consensus. A steering committee developed 9 statements related to SCBs for the treatment of focal epilepsy, and these statements were evaluated and voted upon by the expert panel. RESULTS: The expert panel achieved consensus on nine statements regarding the treatment recommendations for oxcarbazepine, lamotrigine, lacosamide, eslicarbazepine, topiramate, zonisamide and cenobamate in focal epilepsy patients and treatment adjustments for SCBs. CONCLUSION: This is a Chinese expert consensus on the use of SCBs in focal epilepsy developed using the modified Delphi method. These recommendations can help clinicians in their practice and guide future research.
Source: Seizure
Authors: Raowei Yan, Hesheng Zhang, Zhen Hong, Weiping Liao, Xuefeng Wang, Yuping Wang, Bo Xiao, Yanchun Deng, Meiping Ding, Xiong Han, Shuli Liang, Weihong Lin, Xiaorong Liu, Xuewu Liu, Xin Wang, Tiancheng Wang, Xiangqing Wang, Xiaoshan Wang, Peimin Yu, Kai Zhang, Jian Zhou, Liemin Zhou, Shuizhen Zhou, Guoxing Zhu, Suiqiang Zhu, Xintong Wu, Dong Zhou
Institutions: West China Hospital of Sichuan University, Shanghai Medical College of Fudan University, Fudan University, Huashan Hospital, Second Affiliated Hospital of Guangzhou Medical University, Chinese PLA General Hospital, Nanjing Brain Hospital, Zhongshan Hospital, The Affiliated Yongchuan Hospital of Chongqing Medical University, First Affiliated Hospital of Chinese PLA General Hospital, Nanjing Medical University, Capital Medical University, Xuan Wu Hospital of the Capital Medical University, Central South University, Xiangya Hospital Central South University, Second Affiliated Hospital of Zhejiang University, Zhejiang University, Henan Provincial People's Hospital, Beijing Children’s Hospital, First Hospital of Jilin University, First Bethune Hospital of Jilin University, Shandong Provincial Hospital, Shandong First Medical University, Lanzhou University Second Hospital, Lanzhou University, Beijing Tian Tan Hospital, Beijing Sanbo Brain Hospital, The Seventh Affiliated Hospital of Sun Yat-sen University, Children's Hospital of Fudan University, Tongji Hospital, Huazhong University of Science and Technology
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $2,970
OpenAlex ID: W4408360172