“Unveiling the Anti-Diabetic Potential of Lindernia ciliata by using in-vitro methods: Phytochemical Insights and Mechanistic Pathways"
Year: 2025
Type: article
Abstract: Objective: To evaluate the phytochemical screening and anti-diabetic activity of different fractions obtained from the hydroalcoholic extract of Lindernia ciliata (Colsm.) Pennell. Methodology: The hydroalcoholic extract of L. ciliata, a member of the Linderniaceae family, was fractionated using petroleum ether, chloroform, methanol, and water. These fractions were analyzed for secondary metabolites through phytochemical screening, and the total phenolic and flavonoid contents were determined. The anti-diabetic activity of the fractions was assessed using multiple assays, including glucose absorption, glucose uptake, insulin secretion by RIN-5F cells, α-amylase inhibition, and DPP-4 inhibition.
Source: Cuestiones de Fisioterapia
DOI: 10.48047/nkfmqv13
Authors: ANJU DAS, GEETHA K M
Institution: Dayananda Sagar University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4408372931