Gastrodia elata as a Neuroprotective Agent: A Mini-review of its Bioactive Compounds and Mechanisms of Action
Year: 2025
Type: review
Abstract: Gastrodia elata commonly called Tianmab is a traditional medicinal herb widely used in East Asia for its purported neuroprotective effects. This mini-review summarizes the current understanding of the bioactive compounds within G. elata and their potential mechanisms of action related to neuroprotection. Evidence suggests that compounds like gastrodin, gastrodial, and parishin exhibit antioxidant, anti-inflammatory, and anti-apoptotic properties, contributing to the protection of neuronal cells against various stressors. Further research is needed to fully elucidate the specific pathways involved and to translate these findings into clinically relevant applications for neurodegenerative diseases and other neurological disorders.
Authors: UDI, OA, OMURUKA, TC
Institution: Federal University Otuoke
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408409242