Work

Utility of 18F-FDG PET/CT and Cardiac MRI in early Cardiac Sarcoidosis

Year: 2025

Type: article

Abstract: BACKGROUND AND AIMS: F-FDG-PET/CT) and cardiac magnetic resonance imaging(CMR) in patients with early- and late-stage CS. METHODS: F-FDG0PET/CT and CMR within 2 weeks of initial clinical presentation. Patients were divided into early-(<6 months) and late-stage groups based on the time since their first cardiac presentation. Myocardial uptake and late gadolinium enhancement(LGE) were qualitatively and quantitatively assessed. Complete clinical, echocardiographic, and radiological responses were assessed after 4-6 months of immunosuppressive therapy(IST). RESULTS: and more extensive LV involvement than those with late CS. Complete response to IST was more common in patients with early CS than in those with late CS(62.5 %vs.47.8 %,p = 0.019). In the early CS cohort, patients without LGE had a higher rate of complete response following IST than those with LGE (86.7 %vs.53.7 %,p = 0.025). CONCLUSION: F-FDG-PET/CT appears to be more sensitive and useful than CMR for diagnosis and assessment of response to IST.

Source: Indian Heart Journal

DOI: 10.1016/j.ihj.2025.03.007