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Localizing dorsolateral prefrontal cortex for noninvasive brain stimulation in adolescents: A comparison between BeamF3 and 10–20 EEG systems: A cross-sectional study

Year: 2025

Type: article

Abstract: Background: The dorsolateral prefrontal cortex (DLPFC) is implicated in neuropsychiatric disorders. It is a primary target region for noninvasive brain stimulation (NIBS). BeamF3 is a simplified method of localization of DLPFC for neuromodulation. However, the accuracy of this method has not been examined in children. Aim: To compare the localization of DLPFC via BeamF3 and 10-20 electroencephalogram (EEG) systems in adolescents with neuropsychiatric disorders. Methods: Twenty adolescents (10-15 years) were recruited from the in-patient child and adolescent psychiatry unit of our center. DLPFC localization was done and compared between the BeamF3 and 10-20 EEG systems. DLPFC localization based on the BeamF3 method at anterior/anterolateral/lateral position was compared with 10-20 EEG systems in 70% of adolescents. Results: The mean difference in DLPFC localization was 1.10 ± 0.81 cm (0-3 cm), with a difference of ≥1 cm in 70% of adolescents. This study found a difference between Beam F3 and 10-20 EEG systems in terms of localization of DLPFC in adolescents. Conclusion: Comparison of these methods with MRI-guided methods may be necessary, especially when highly focal stimulation is desired for treatment in adolescents.

Source: Indian Journal of Psychiatry

DOI: 10.4103/indianjpsychiatry.indianjpsychiatry_972_24

Authors: Sakhardande Kasturi Atmaram, Harsh Pathak, Harshini Manohar, Vanteemar S. Sreeraj, Ganesan Venkatasubramanian, John Vijay Sagar Kommu

Institution: National Institute of Mental Health and Neurosciences

Language: English

Topic: Transcranial Magnetic Stimulation Studies

Subfield: Neurology

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Wellcome Trust