Year: 2024
Type: article
Study design: Case Report
Abstract: Hepatoid adenocarcinoma (HAC) is a rare and aggressive malignancy with histological and immunohistochemical features resembling hepatocellular carcinoma originating from non-hepatic organs. We report a case of HAC in a 34-year-old male, arising from the transverse colon, with metastases to the stomach, liver, lungs, and right femur. He presented with persistent anaemia and sub-acute intestinal obstructive symptoms. Laparotomy confirmed a transverse colon tumour infiltrating the stomach, accompanied by hepatic and peritoneal lesions. He underwent extended right hemicolectomy and en-bloc resection of the distal stomach, with a histopathological diagnosis of hepatoid adenocarcinoma. Subsequently, he suffered a pathological hip fracture and was treated with open reduction and internal fixation, followed by radiotherapy and palliative adjuvant chemotherapy. The disease progressed, leading to thoracic spine bone metastasis, necessitating further radiotherapy. He is alive, eight months post-surgery, despite a poor prognosis and disease progression
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408450145