Work

In vivo HSC transduction in humanized mice mediated by novel capsid-modified HDAd vectors

Year: 2025

Type: article

Abstract: HSC transduction with HDAds, with implications for studies with other vectors.

Source: Molecular Therapy — Methods & Clinical Development

DOI: 10.1016/j.omtm.2025.101448

Authors: Aphrodite Georgakopoulou, Hongjie Wang, Jiho Kim, Chang Li, André Lieber

Institutions: University of Washington, PAI Life Sciences (United States)

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900

Funders: Bill and Melinda Gates Foundation, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, NHLBI Division of Intramural Research, Grand Challenges in Global Health

Awards: G2670169348, G5307391243, G7083559132, Stem Cell and Transplantation Biology

OpenAlex ID: W4408462146

FWCI: 4.276

Cites: 41

Cited by: 8

Related to: 10