Work

Association between triglyceride-glucose index and the risk of stroke among moyamoya patients: a single-center retrospective study

Year: 2025

Type: article

Abstract: Background: Moyamoya disease increases the risk of strokes by impairing cerebral circulation, significantly affecting patients' quality of life. Despite the profound implications of this condition, there is a limited body of research exploring the factors that contribute to strokes in patients with Moyamoya disease. This study aims to evaluate the predictive value of the triglyceride-glucose index (TyG index) in forecasting stroke events among individuals diagnosed with moyamoya disease. Methods: A total of 84 patients diagnosed with Moyamoya disease were treated at Changshu First People's Hospital from 01 January 2019 to 31 October 2024 were included in this study. We systematically collected and analyzed their clinical histories, laboratory test results, and baseline data. The patients were classified into two groups based on their history of cerebral stroke. Subsequently, we conducted a comparison and analysis of the TyG index between these two groups. Results: < 0.05). Furthermore, regression cubic splines analysis indicated a noteworthy linear relationship between the TyG index and the occurrence of cerebral stroke events. Conclusion: In individuals diagnosed with Moyamoya disease, the TyG index has been shown to have a significant correlation with the risk of cerebral stroke. Furthermore, it has the potential to serve as an effective predictor for the occurrence of stroke.

Source: Frontiers in Neurology

DOI: 10.3389/fneur.2025.1547627

Authors: Chi Zhang, Kai Guo, Hong Xu, Gang Kong, Chuanghong Liu

Institution: Changshu No.1 People's Hospital

Language: English

Topic: Moyamoya disease diagnosis and treatment

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801