Kinetic Study of Aquo-Ethylene Glycol on Alkali Catalyzed Hydrolysis of Heterocyclic Acid Ester Methylpicolinate and Thermodynamic Activation Parameters
Year: 2025
Type: article
Abstract: A kinetic investigation was conducted to analyze the thermodynamic parameters of the hydrolysis of Methylpicolinate in water-Ethylene glycol solvent system, using different concentration of Ethylene glycol (v/V) at four different temperature 200C, 250C, 300C, and 350C. The influence of the solvent on the reaction rate was analyzed in terms of activation parameters. The decreasing trend in ΔH* and ΔS* values, coupled with the rising ΔG* with increasing concentration (mole %) of the organic co - solvent in the reaction media, inferred an enthalpy-dominated and entropy-controlled reaction. The evaluated value of Isokinetic temperature is very close to 300, suggesting the presence of weak but positive interaction between solvent and solute present in the reaction media
Author: Shalini Kumari
Institution: Patna University
Language: English
Topic: Chemical Reaction Mechanisms
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4408479281