Malignant Hypertension Mimicking Pulmonary-Renal Syndrome
Year: 2025
Type: article
Study design: Case Report
Abstract: Pulmonary renal syndrome (PRS) is a rare clinical syndrome characterized by pulmonary hemorrhage and rapidly progressing glomerulonephritis. It is commonly due to a rheumatologic etiology, including antineutrophil cytoplasm antibodies vasculitis or antiglomerular basement membrane disease. Given the rapid progression, patients are often empirically treated when there is high clinical suspicion for PRS. Few case reports have shown malignant hypertension (HTN) as a mimicker of PRS. We present a case of a patient with dyspnea, hemoptysis, and hematuria where there was high suspicion for PRS, and immunosuppression was initiated, but in the end, the etiology was malignant HTN. Malignant HTN can lead to multiple end-organ damage, including the lungs and kidneys; thus, it is important to consider malignant HTN in the differential. Overall, we report a case of malignant HTN mimicking PRS.
Source: Cureus
DOI: 10.7759/cureus.80654
Authors: Shannon M Lee, Aida F Martinez, Nathan Yee
Institutions: Los Angeles Medical Center, Harbor–UCLA Medical Center
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408489192