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Delayed malignant appendiceal fistula with ileal conduit following radical cystectomy: A case report

Year: 2025

Type: article

Abstract: Fistula formation after radical cystectomy is rare, often presenting early and involving the small bowel. Herein we describe a case of an appendiceal fistula in a patient who underwent chemoradiotherapy and pelvic exenteration over a decade prior to the presentation of their fistula. Initially suspected to be radiation-induced, final pathology revealed a mucinous neoplasm of the appendix, which had fistulized with the ileal conduit. This case emphasizes the importance of considering alternative causes, such as malignancy, in delayed fistulas, especially in patients with prior radiation. Clinicians should maintain high suspicion for appendiceal neoplasms to guide proper preoperative and intraoperative planning.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2025.103008

Authors: Benjamin H. Dalkin, Beau B. Toskich, Dorin T. Colibaseanu, Young Erben, Timothy D. Lyon

Institutions: Mayo Clinic, Mayo Clinic in Florida

Language: English

Topic: Intraperitoneal and Appendiceal Malignancies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160