Work

Cerebral venous thrombosis caused by short‐term administration of ethinylestradiol and cyproterone acetate tablets in adolescents: A case report

Year: 2025

Type: article

Abstract: It is very rare for teenagers to suffer from cerebral venous thrombosis due to oral contraceptives in a short period. Here, we report a 14-year-old girl who developed superior sagittal sinus thrombosis 2 days after oral ethinylestradiol and cyproterone acetate tablets treatment for abnormal uterine bleeding. There were no recorded instances of coagulopathies or strokes in her family or personal medical history. After admission, she experienced two convulsions and was administered diazepam for treatment. Anticoagulant therapy with low-molecular-weight heparin was initiated concurrently. After spending 12 days at our facility receiving medical care, she could be discharged home successfully. Although the risk of thrombosis in adolescent patients is extremely low, clinicians should conduct a comprehensive assessment of patients when taking drugs, and good insight into drug use and actual adverse drug reactions is essential to minimize the risk in practice.

Source: Journal of obstetrics and gynaecology research

DOI: 10.1111/jog.16261

Authors: Huayu Han, Cuiyan Wang, Yang Yue, Wei Liu

Institutions: Shandong Provincial Hospital, Shandong First Medical University

Language: English

Topic: Cerebral Venous Sinus Thrombosis

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Shandong First Medical University, Key Technology Research and Development Program of Shandong