Work

Rapidly fatal anaplastic CD30+ primary cutaneous T-cell lymphoma: about a case

Year: 2025

Type: article

Abstract: CD30+ anaplastic primary cutaneous T-cell lymphoma is a type of cutaneous lymphoma rarely described in the literature and has an exceptional disseminated tumor form. This was a 73-year-old man who presented with nodular skin tumors whose size exceeded 5 cm, firm, painless, secondarily ulcerated, becoming ulcerative budding with a necrotic-purulent background and very painful. These lesions were located on the lower limbs, predominant on the right. Extra-dermatological examination found: right satellite tumor macropolyadenopathy, popliteal, inguinal, axillary and cervical. The rest of the physical examination was normal. Immunostained skin histopathology led to the diagnosis of CD30-positive anaplastic T-cell lymphoma. The course was quickly fatal despite the chemotherapy treatments. The case we report illustrates the diagnostic and therapeutic problem of cutaneous T-cell lymphomas that are still intact in our context of practice in Africa by the absence of immunotherapy and the side effects of chemotherapy which weigh on the patient's prognosis apart from the aggressiveness of the disease itself. Keywords: CD30+ cutaneous T-cell lymphoma, tumor skin lesions, case report.

Source: Journal of African clinical cases and reviews.

DOI: 10.70065/2591.jaccrafri.003l011503