Work

Colovesical Fistula and Amyloidosis

Year: 2025

Type: article

Abstract: Systemic amyloidosis results from an abnormal deposition of toxic insoluble beta-sheet fibrillar protein in extracellular tissues, causing damage to multiple organ systems. Amyloid proteins (e.g., transthyretin, light chains, and serum amyloid A) may infiltrate the mucosa or vascular structures, resulting in gastrointestinal manifestations, including bleeding and diarrhoea. We discuss a case of a 71-year-old male with systemic immunoglobulin G kappa amyloid light chain amyloidosis who developed a colovesical fistula related to amyloid deposition.

Source: Cureus

DOI: 10.7759/cureus.80695

Authors: Samantha Leng, Wei Ming Ong, Reizal Mohd Rosli, Tarini Fernando, Vinna An

Institution: Eastern Health

Language: English

Topic: Amyloidosis: Diagnosis, Treatment, Outcomes

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408500346

FWCI:

Cites: 7

Cited by:

Related to: 10