Work

Myocarditis

Year: 2025

Type: article

Abstract: Antiphospholipid syndrome (APS) is known for thrombotic events and pregnancy complications, but its association with myocarditis is rare and poorly understood. A 44-year-old woman presented with acute chest tightness, elevated cardiac biomarkers, and severe anemia. Diagnostic workup revealed ST-segment changes on electrocardiogram, preserved left ventricular function on echocardiography, and myocardial inflammation on cardiac magnetic resonance imaging, suggestive of acute myocarditis. Positive antiphospholipid antibodies confirmed APS. She was managed with close multidisciplinary follow-up. APS-associated myocarditis poses diagnostic challenges because of its atypical presentation and overlap with other cardiac conditions. This case highlights the role of cardiac magnetic resonance imaging in diagnosing myocarditis early, guiding management strategies, and the need for heightened clinical suspicion in APS patients presenting with cardiac symptoms.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2024.102667

Authors: Alexander C. Sacher, Rafsan Ahmed, Andrew Kung, Jasneel Kahlam

Institution: New York Hospital Queens

Language: English

Topic: Viral Infections and Immunology Research

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $850