Work

Predictors of Health-related Quality of Life in Temporomandibular Disorder Patients: 8-year Cohort Study

Year: 2025
Type: article
Study design: Observational Study
Abstract: • An 8-year follow-up study of 392 participants analyzed HRQoL in TMD using the SF-12. • Healthy controls: JFLS predicted mental HRQoL (MCS) but not physical HRQoL (PCS). • Nonpainful TMD: JFLS and general health predicted PCS, but no factors predicted MCS. • Painful TMD: Age and general health predicted PCS, while no factors predicted MCS. This study aimed to identify baseline factors that predict Health-Related Quality of Life (HRQoL) in patients with TMD 8 years later. 401 participants (333 women, mean age 45.8 years) from a multicenter cohort were examined using the Diagnostic Criteria for TMD (DC/TMD) and questionnaires. The main outcome was the 12-item Short Form Health Survey (SF-12), a HRQoL measure that provides physical (PCS) and mental (MCS) summaries. Baseline predictors included age, gender, self-reported health, Jaw Functional Limitation Scale (JFLS), pain intensity, pain frequency, and pain duration. Regression analysis with stepwise modeling identified predictive factors. 54.3% had painful TMD, 15.7% had nonpainful TMD, and 27.7% were healthy controls. For the painful TMD group, the regression model was significant ( R² = .25, F = 4.3, P < .01), with age and favorable general health predicting PCS scores. In the nonpainful TMD group, the model was significant ( R² = .58, F = 3.8, P < .01), with JFLS and favorable general health (predicting PCS scores. The MCS model was significant in healthy controls ( R 2 = .22 , F = 1.8 , P = . 05 ), with JFLS as only predictor. Predictors of mental HRQoL: JFLS in healthy controls, but no predictors were found in TMD groups. Predictors of physical HRQoL: General health in both TMD groups, JFLS in the nonpainful TMD group, and age in the painful TMD group.
Language: English
Open Access status: hybrid
Estimated APC paid: $4,030
OpenAlex ID: W4408514479
FWCI: 0.985
Cites: 46
Cited by: 1
Related to: 10