Imine Reductase-Catalyzed Synthesis of a Key Intermediate of Avacopan: Enzymatic Oxidative Kinetic Resolution with Ex Situ Recovery and Dynamic Kinetic Reduction Strategies toward 2,3-Disubstituted Piperidine
Year: 2025
Type: article
Authors: Zsuzsa Juhász Pótáriné, Tihamér Paál, Lajos Mészáros, Gergely Bánóczi, Zoltán Kondor, Napsugár Kavalecz, Andrea Zsuzsanna Ujvárosi, János Végh, Dániel Eszenyi, Gábor J. Zahuczky, Ram Prajapaty, Rushikesh Kadu, Vadivelan Rengasamy, Imre Gyűjtő
Institution: Teva Pharmaceuticals (Hungary)
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: closed
OpenAlex ID: W4408518037