Work

Author response: A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits

Year: 2025

Type: peer-review

Abstract: A differentiable variant of the Gillespie algorithm enables gradient-based optimization for stochastic chemical kinetics, facilitating efficient parameter estimation and the design of biochemical networks with desired input–output relationships.

DOI: 10.7554/elife.103877.3.sa4

Authors: Krishna Rijal, Pankaj Mehta

Institution: Boston University

Language: English

Topic: Gene Regulatory Network Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W4408522719

Cites:

Cited by:

Related to: 10