Work

Exploring the Multifunctionality of Passiflora caerulea L.: From Traditional Remedies to Modern Applications

Year: 2025

Type: article

Abstract: Medicinal plants are well-known for synthesizing a wide range of bioactive compounds used mainly in the pharmaceutical, food and cosmetic industries. The therapeutic use of Passiflora species in Europe began in the 17th century, but few studies have been carried out on Passiflora caerulea L. This is a versatile plant, an herbaceous climber, belonging to the Passifloraceae family. In the past, P. caerulea L. has been mainly used as a sedative agent, but in recent years, scientific studies have focused on exploring its functionality and pharmacological use. Phytochemical analysis has revealed several classes of phytochemical components, some of which have promising biological potential. Recent studies have confirmed the therapeutic potential of P. caerulea by demonstrating its in vivo anxiolytic and antistress effects as well as antimicrobial, antioxidant, anticonvulsant, analgesic and gastroprotective activities. While these findings have been encouraging, there has been limited research conducted on the on the phytochemical profiling, biosafety and molecular mechanisms of the biological activity of extracts from Passiflora caerulea L. This review aims to summarize and analyze the recent scientific data on biological activities of Passiflora caerulea, including phytochemical profiling, mechanisms of action of individual compounds and potential therapeutic applications.

Source: Applied Sciences

DOI: 10.3390/app15063251

Authors: Alexandra Garmidolova, Pervin Halkoglu-Hristova, Vasil Georgiev

Institution: Bulgarian Academy of Sciences

Language: English

Topic: Medicinal Plant Extracts Effects

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,896