The Impact of Two Platelet Concentrates on Healing of Surgically Created Bone Defects in Sheep (Radiological Analysis)
Year: 2025
Type: article
Abstract: The present study aims to assess the density of bone with Concentrated growth factors and advanced plasma-rich fibrin in the bone defects that were created surgically in the sheep's mandible by the use of radiographic assessment.Materials and methods: Seven defects were made in the bone with 4 mm depth and width on every side of the mandible of the eight sheep, The defects were filled in the following manner: from the proximal to the distal orientation; 1 st , 2 nd , 3 rd , 4 th , and the 5 th defect was full of CGF on the right side and A-FRF is in the left side, the 6 th , and 7 th left empty to filled with physiological clot.Densitometric analysis of the defects of the bone was made to measure the bone density of the 4 intervals (3 days, 7 days, 21 days, 28 days), after the surgery.Results: The result of the Densitometric analysis revealed a major distinction between the CGF group and the A-PRF group when compared to the control group at all four intervals with the density of the bone being the highest in the CGF group followed by the A-PRF group and the control group was the least one show improvement in the bone density.Conclusions: The CGF group increased the density of the bone throughout the entire study period as found by densitometric analysis data.
Authors: Amina Abdolfattah Humadi, Rayan Salim Hamed, Hayam Nori Awad
Institutions: University of Mosul, University of Duhok
Language: English
Subfield: Urology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
Funder: University of Mosul
OpenAlex ID: W4408538659