Work

Insights into the DNA damage response and tumor drug resistance

Year: 2025

Type: article

Abstract: DDR is a highly coordinated signaling network that repairs DNA damage caused by intrinsic cellular processes and extrinsic insults, thereby preventing genome instability. Depending on the type of damage, distinct DNA damage repair and DNA damage tolerance (DDT) pathways are involved and coordinately

Source: Cancer Biology and Medicine

DOI: 10.20892/j.issn.2095-3941.2025.0020

Authors: Xiaolu Ma, Zina Cheng, Caixia Guo

Institutions: Taiyuan University of Technology, Chinese Academy of Sciences, Beijing Institute of Genomics, University of Chinese Academy of Sciences

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,500