Work

Physical exercise and anti-inflammatory agents in an animal model of seizures

Year: 2025

Type: article

Abstract: A previous study revealed the protective effect of an aerobic exercise protocol on behavioral and inflammatory aspects in an animal model of epileptic seizures. The previously collected samples in that investigation were now analyzed from the perspective of oxidative stress. Five experimental groups of Wistar rats were used (sedentary, diazepam, two physical exercise groups, and naive). Analyzes of lipid peroxidation, sulfhydryl content levels, and quantification of reduced glutathione were performed in the cortical and hippocampal tissues of the animals. There was no change in any parameter in any of the analyzed tissues.

Source: Journal of Health & Biological Sciences

DOI: 10.12662/2317-3076jhbs.v13i1.5510.p1-3.2025

Authors: Gabriel de Lima Rosa, Edson Muller Guzzo, Silvia Elisandra Bitello Nunes, Jéssica Lamberty Faverzani, Rafael Bremm Padilha, Amanda Muliterno Domingues Lourenço de Lima, Brayan Braz Barbosa, Carmen Regla Vargas, Ionara Rodrigues Siqueira, Adriana Simon Coitinho

Language: English

Topic: Epilepsy research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408556898

FWCI:

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