A Case Report of Cardiac Ascites in Morquio Syndrome Complicated by Pulmonary Hypertension
Year: 2025
Type: article
Study design: Case Report
Abstract: Morquio syndrome, or mucopolysaccharidosis type IV (MPS IV), is a rare lysosomal storage disorder characterized by skeletal dysplasia and dysostosis multiplex. While primarily associated with skeletal manifestations, MPS IV can also affect systemic organs. Here, we present a case of a 64-year-old woman with MPS IVC who presented with cardiac ascites. The patient's disease course was characterized by idiopathic pulmonary hypertension to cor pulmonale and subsequent cardiac ascites formation. Utilizing paracentesis with cytology as well as an analysis of the patient's clinical history and disease progression, we provide insights into the interplay between Morquio syndrome and cardiac ascites.
Authors: Gauri Patel, Olakanmi Joseph Deleawe
Institutions: Kansas City University, Mercy Hospital
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408559516