Effectiveness of modern statin therapy (clinical case)
Year: 2024
Type: article
Study design: Case Report
Abstract: Aim. The study is intended to research the regression of atherosclerotic plaques in carotid arteries based on the example of a specific clinical case, to justify the need to take statins to prevent cardiovascular diseases, and to increase life duration and quality. Materials and methods. Phillips Affiniti 70 Expert Grade Ultrasonic Diagnostic Apparatus using a linear L12-3 sensor with an extended operating frequency range of 3–12 MHz for vascular examination. Ultrasound duplex scans of the patient's carotid arteries, the medical history of a new coronavirus infection, the conclusions of specialists and the results of a lipidogram over 1.5 years over time were analyzed. Results. The results of these research show an urgent need to take statins by patients in the group of high and very high risk of cardiovascular diseases. Significant regression of atherosclerotic plaque up to the thickening of the intima-media complex due to long-term adherence to the patient's therapy and close cooperation with the treating physician is shown on the example of one specific case. Conclusion. Cardiovascular diseases are one of the leading causes of death in the world. Our study emphasizes that statins are the "gold standard" in reducing the level of hypercholesterolemia as they change the morphological composition of atheroma an strengthen its fibrous membrane. They also increase resistance to rupture by reducing its volume, along with regressing stenoses in the carotid arteries and finely decrease mortality. All said above, confirms the relevance of our study. In this regard, the purpose of our work is to prove the regression in the lumen of carotid artery stenosis.
Authors: Arina L. Lushchik, Olga A. Zemlianukhina, Olga A. Panina, Irina A. Firsova, Vladislav N. Kalaev
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408574525