Year: 2025
Type: article
Abstract: Allergy to mammalian meat is caused by IgE-mediated reactions to the mammalian oligosaccharide epitope galactose-α-1,3-galactose (αGal). The αGal epitope is present on glycoproteins and glycolipids from non-primate mammals, including cat and dog.1,2 Allergen extracts are the current standard for the diagnosis and treatment of allergy.3 These allergenic source materials (eg, pet hair and dander) comprise a heterogeneous mixture of mammalian proteins, including the major and minor allergens, as well as nonallergenic proteins, which could contain αGal.
Authors: Tina K. Merritt, Max D. Bermingham, Sayeh Agah, Rhys T. Meredith, Bryan R.E. Smith, Martin D. Chapman
Language: English
Subfield: Immunology and Allergy
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,000
OpenAlex ID: W4408590765