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Tirzepatide as an Emerging Modality for Management of Obstructive Sleep Apnea

Year: 2025

Type: article

Abstract: The recent randomized controlled trial (RCT) SURMOUNT-OSA evaluated the role of tirzepatide in the management of obstructive sleep apnea (OSA).The drug was found to reduce body mass index (BMI), apnea-hypopnea index, and total area under the oxygen dissociation curve during apnea or the apnea-related "hypoxic burden".The trial has brought out a few key findings that have a potentially substantial impact on the management of OSA in obese individuals.This review article is aimed at the new emerging modality of OSA management, i.e., weight reduction as a potential first-line treatment.

Source: Indian Journal of Sleep Medicine

DOI: 10.5005/jp-journals-10069-0151

Authors: Dipti Gothi, Pranav Ish, Nipun Malhotra

Institutions: Employees State Insurance Post Graduate Institute of Medical Sciences and Research, Safdarjang Hospital, Vardhman Mahavir Medical College & Safdarjung Hospital

Language: English

Topic: Obstructive Sleep Apnea Research

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408617715

FWCI:

Cites: 6

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Related to: 10