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Serpiginous plaques: An atypical presentation of secondary syphilis in human immunodeficiency virus

Year: 2025

Type: article

Abstract: Syphilis is known to run its natural course unless intervened, and the severity of clinical presentation in human immunodeficiency virus (HIV) co-infection is well established. Here, we report the case of a 47-year-old male on antiretroviral therapy for 9 years, who presented with a persistent serpiginous plaque over the neck, along with painless genital ulcers and painful oral ulcers. These lesions resolved rapidly after three doses of benzathine penicillin with subsequent follow-up showing declining Venereal Disease Research Laboratory titers. This case highlights the atypical presentation of syphilis and the need for a high index of suspicion while approaching cutaneous manifestations in HIV.

Source: Journal of Skin and Sexually Transmitted Diseases

DOI: 10.25259/jsstd_93_2024

Authors: Sudhesshna Devi, Ramesh M. Bhat

Institutions: Saveetha University, Father Muller Medical College Hospital

Language: English

Topic: Syphilis Diagnosis and Treatment

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408622927

FWCI:

Cites: 15

Cited by:

Related to: 10