Work

[Factors associated with prognosis and treatment failure in children with acute lymphoblastic leukemia].

Year: 2025

Type: other

Abstract: OBJECTIVES: To explore the factors related to prognosis and treatment failure in children with acute lymphoblastic leukemia (ALL). METHODS: A retrospective study was conducted to collect and analyze clinical data of ALL children admitted to the Department of Pediatric Hematology at Tongji Hospital, Huazhong University of Science and Technology, from January 2012 to December 2019, with follow-up until June 2024. RESULTS: <0.05). CONCLUSIONS: The prognosis of children with ALL is related to risk stratification, immunophenotyping, relapse status, and occurrence of severe adverse events. Among these factors, relapse is the primary cause of treatment failure. Actively preventing relapse may reduce the treatment failure rate and improve long-term survival.

Source: PubMed

DOI: 10.7499/j.issn.1008-8830.2409008

Authors: Meng-Meng Yin, Qun Hu, Ai-Guo Liu, Ya-Qin Wang, Ai Zhang

Institutions: Tongji Hospital, Huazhong University of Science and Technology

Language: English

Topic: Acute Lymphoblastic Leukemia research

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4408649234

Cites: 15

Cited by:

Related to: 10