A Case Report on an Uncommon Presentation of Giant Cell Tumor of the Tendon Sheath in the Infrapatellar Region
Year: 2025
Type: article
Study design: Case Report
Abstract: Giant cell tumor of the tendon sheath (GCT-TS) is a benign yet locally aggressive soft tissue neoplasm that typically arises in synovium-lined structures, including tendon sheaths, bursae, and joints. Also known as localized nodular tenosynovitis, this tumor primarily affects the hands and fingers but can occur in other anatomical locations. GCT-TS is histologically characterized by multinucleated giant cells within a background of mononuclear stromal cells. While it is generally nonmetastatic, the tumor carries a risk of local recurrence following surgical removal. Recognizing the clinical presentation, histopathological features, and appropriate management strategies is essential for effective treatment and recurrence prevention. Here, we present the case of a 34-year-old woman with a one-year history of pain in the infrapatellar region. Imaging revealed a well-defined soft tissue mass posterior to the patellar tendon, which was surgically excised. Histopathological examination confirmed the diagnosis of nodular-type GCT-TS. The patient's symptoms resolved completely postoperatively, and no recurrence was observed during a five-year follow-up period, highlighting the effectiveness of surgical excision in managing this rare tumor location.
Source: Cureus
DOI: 10.7759/cureus.80918
Authors: Arın Celayir, Hasan Marangoz, Gamze Göktürk Özcan, Nuraddin Abdullaev, Vedat Burkay Camurdan, Bedri Karaismailoglu
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408665934