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Hands-on Guide to Sample Size Calculation in Medical Research Using EZR

Year: 2025

Type: article

Abstract: Sample size calculation is an important part of any medical research. The statistical analysis will provide valid inference only when the sample size is adequate enough to answer the research question. A small sample size may produce inconclusive results and too large sample size will waste the resources and could expose more participants than necessary. Hence the proper estimation of minimum required sample size for research is an important step in the design of any study. The present article gives an introduction to the various aspects of sample size estimation with hypothetical examples along with step-by-step illustration using EZR software.

Source: Journal of Complementary and Alternative Medical Research

DOI: 10.9734/jocamr/2025/v26i3639

Authors: Amitha Puranik, Kalesh M Karun, Deepthy MS

Institutions: Manipal Academy of Higher Education, Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research

Language: English

Topic: Statistical Methods in Epidemiology

Subfield: Statistics and Probability

Field: Mathematics

Domain: Physical Sciences

Open Access status: diamond

OpenAlex ID: W4408724321

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