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Synthesis and characterization of novel PIPERIDINYL-methyl-PURINEAMINE derivatives

Year: 2025

Type: article

Abstract: Piperidinyl methyl purine amines are the biologically active compounds, which exhibit different biological activities; we here in reported the purine amine derivatives from bromo fluoro isonicotinate in six steps, which involves, Suzuki coupling, SNAr reaction with different amines, reduction, chlorination, regioselective substitution and deprotection reactions. All the compounds characterized by using 1 H NMR, 13 C NMR and mass spectral analysis.

Source: Results in Chemistry

DOI: 10.1016/j.rechem.2025.102213

Authors: Srinivasa Reddy Keesara, Ratnasekhar Bolla, Hanumantharayappa Bharathkumar, Ramya Chilukuri, Sreedhar Gundekari, Mohan Varkolu

Institutions: Koneru Lakshmaiah Education Foundation, Indian Institute of Chemical Technology

Language: English

Topic: Synthesis and Characterization of Heterocyclic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,870

OpenAlex ID: W4408725553

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Cites: 19

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Related to: 10