Work

SFC-MS/MS enantioseparation, stereoselective behavior and risk assessment of the chiral pesticide bitertanol in four vegetables and soil

Year: 2025

Type: article

Abstract: The stereoselective behavior and dietary risk of bitertanol in four vegetables and soil were studied. Firstly, the method for measuring bitertanol stereoisomers by SFC-MS/MS was established and optimized, and the analysis time was 5 min. In addition, cis-(+)-(1R,2S)-bitertanol and trans-(+)-(1R,2R)-bitertanol were preferentially dissipated in cabbage and pakchoi, while trans-(+)-(1S,2S)-bitertanol had a preferential dissipation in lettuce. For diastereoisomers, cis-bitertanol was dissipated with preference in the vegetables under test. The dissipation halflives of rac-bitertanol were as follows: pakchoi (0.57-0.74 days) < cabbage (0.87-1.07 days) < celery (1.32-1.63 days) < lettuce (1.75-2.37 days) < soil (22.5-24.7 days). Finally, the final residual concentrations of rac-bitertanol in lettuce (0.0128 mg/kg) and celery (0.0289 mg/kg) were higher than the maximum residue limit (MRL, 0.01 mg/kg), which should raise concern. The results of dietary risk assessment showed that both the chronic dietary risk and the acute dietary risk of rac-bitertanol in these test vegetables were negligible.

Source: Food Chemistry

DOI: 10.1016/j.foodchem.2025.143943