61MO Perceptions of healthcare professionals and regulators on the use of real-world data as external comparators in late-stage oncology single-arm trials
Year: 2025
Type: article
Abstract: Real-world data (RWD) have potential applications for complementing other data sources, including as external comparators for single-arm trials (SAT). We aimed to explore perceptions about this methodology in the setting of advanced cancer of high unmet medical need.
Source: ESMO Open
Authors: D. Martins-Branco, D. Postmus, T.C. El-Galaly, A. Valachis, D. Trapani, M. Di Maio, P. Mol, K. Porkka, K. Robertson, U-P. Rohr, R. Doeswijk, M. Kaiser, M. Koopman, N. Cherny, R. Cordoba, G. Pentheroudakis, F. Pignatti
Institutions: European Society for Medical Oncology, European Medicines Agency, University Medical Center Groningen, Aarhus University Hospital, Örebro University Hospital, European Institute of Oncology, University of Turin, Medicines Evaluation Board, University of Helsinki, Swissmedic, European Hematology Association, Institute of Cancer Research, University Medical Center Utrecht, Shaare Zedek Medical Center, Bikur Cholim Hospital, Hospital Universitario Fundación Jiménez Díaz
Language: English
Subfield: Statistics and Probability
Field: Mathematics
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,910
OpenAlex ID: W4408736922