Work

A fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from Cote D′ Ivoire

Year: 2025

Type: article

Abstract: Cryptococcosis is an opportunistic mycosis caused by Cryptococcus , mainly affecting the immunocompromised. We report a case of pulmonary cryptococcosis within a 31-year-old immunocompetent patient admitted for painful chest swelling evolving for 4 months prior to admission. The chest X-Ray showed a rounded pulmonary opacity. The chest ultrasound revealed a pulmonary abscess diffusing under the skin. Direct examination using the Indian ink and the May-Grunwald Giemsa staining revealed encapsulated yeasts in the pus. The Culture of the pus on the Sabouraud medium with chloramphenicol confirmed the presence of Cryptococcus neoformans . Cryptococcal antigen was positive. This case reminds us that cryptococcosis should be considered even without immunosuppression.

Source: Medical Mycology Case Reports

DOI: 10.1016/j.mmcr.2025.100701

Authors: Ahou Sandrine Konan, Kalou Dibert Zika, Affoué Sandrine Josette Kouakou, Appi Sandrine Kouamé, Malick Senanminfoun Soro, Koffi Daho Adoubryn

Institution: Université Alassane Ouattara

Language: English

Topic: Fungal Infections and Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $650