Work

Learning from missteps: Potential of transcranial electrical stimulation in neuropsychological rehabilitation

Year: 2025

Type: article

Abstract: Transcranial electrical stimulation (tES) holds promise for neuropsychological rehabilitation by leveraging the brain's inherent plasticity to enhance cognitive and motor functions. However, early results have been variable due to oversimplified approaches. This manuscript explores the potential and complexities of tES, particularly focusing on a protocol defined transcranial direct current stimulation as a reference model for all tES protocols, emphasising the need for precision in tailoring stimulation parameters to individual characteristics. By integrating intrinsic (i.e. the neuro-physiological system state) and extrinsic factors (i.e. experimental set up), highlighting the critical role of state-dependent effects and the synergy with cognitive tasks, we aim to refine tES protocols. This approach not only addresses the complexity of the brain system (as defined by its current state) but also highlights the importance of collaborative research and data sharing to understand the underlying mechanisms of tES-induced changes and optimising therapeutic efficacy. Emphasising the integration of tES with targeted tasks and clearer hypotheses, this work underscores the potential for more effective neurorehabilitation strategies.

Source: Journal of Neuropsychology

DOI: 10.1111/jnp.12425

Authors: Carlo Miniussi, Maria Concetta Pellicciari

Institutions: University of Trento, Libera Università Maria SS. Assunta

Language: English

Topic: Transcranial Magnetic Stimulation Studies

Subfield: Neurology

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,750