Phenolic profile, antioxidant and antimicrobial activity of Echinophora tenuifolia L. subsp. sibthorpiana
Year: 2025
Type: article
Abstract: In the present study, the phenolic profile, the antioxidant activity, and the antimicrobial activity of an aqueous-methanolic extract prepared from the aerial parts of Echinophora tenuifolia subsp. sibthorpiana growing in Bulgaria were investigated for the first time. The evaluation of the phenolic composition of the extract revealed high levels of total phenols (111.3 ± 9.1 mg GAE/g dry extract) and the presence of the phenolic acids chlorogenic acid, p -coumaric acid, ferulic acid, salicylic acid, rosmarinic acid, the flavonol glycoside rutin, and the flavanone glycoside hesperidin. The highest concentration was observed for rutin (29.625 mg/g). The extract demonstrated good radical scavenging activity in the DPPH assay (IC 50 71.3 ± 0.01 μg/mL) and antioxidant capacity in the ferric-ferrozine assay (405.1 ± 39.9 μmol/g). In addition, the extract exhibited antibacterial activity against E. coli (MIC 1.85 mg/mL, MBC 3.5 mg/mL) and S. aureus (MIC 3.7 mg/mL). In contrast, no antifungal activity against C. albicans was observed.
Source: Pharmacia
Institutions: Medical University Plovdiv, Medical University of Varna
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $107
OpenAlex ID: W4408785693