Work

A platinated prodrug leveraging PROTAC technology for targeted protein degradation and enhanced antitumor efficacy

Year: 2025

Type: article

Source: Inorganic Chemistry Frontiers

DOI: 10.1039/d5qi00605h

Authors: Jiaqian Xu, Shu Chen, Ka-Yan Ng, Xianfeng Chen, Wai Chung Fu, Guangyu Zhu

Institutions: City University of Hong Kong, City University of Hong Kong, Shenzhen Research Institute, University of Edinburgh

Language: English

Topic: Metal complexes synthesis and properties

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: City University of Hong Kong, National Natural Science Foundation of China, Research Grants Council, University Grants Committee, Science, Technology and Innovation Commission of Shenzhen Municipality

Awards: G2791461204, G29494661, G3127769693, 靶向性活化可控铂配合物的设计合成及其对癌细胞的干预机制研究, G5870361467, G6162741341, G7648224127, G7881365906, G8434619901

OpenAlex ID: W4408787742

FWCI: 1.808

Cites: 30

Cited by: 5

Related to: 10