Work

A simple strategy for measuring the genuine resonance Raman optical activity (RROA) of nonpolar molecules

Year: 2025

Type: article

Abstract: Resonance Raman optical activity (RROA) enables increasing very-low analytical sensitivity of ROA, essential for its applications in biomedicine. Since discovery of the ECD-Raman effect, there is discussion if RROA is measurable. Here, we present a straightforward strategy for registration of RROA of nonpolar compounds based on their encapsulation in micelles, enabling nearly complete elimination of the ECD-Raman contribution.

Source: Chemical Communications

DOI: 10.1039/d5cc00879d

Authors: Joanna Mazurkiewicz, Aleksandra Orlef, Tomasz Misiaszek, Tomasz K. Olszewski, Agnieszka Kaczor

Institutions: Jagiellonian University, Wrocław University of Science and Technology

Language: English

Topic: Molecular spectroscopy and chirality

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funder: Narodowe Centrum Nauki

Award: G2925248458