The generation of hydrogen peroxide and antibacterial effectiveness by copper oxide surface layers
Year: 2025
Type: article
Abstract: Copper is known as an antibacterial material.Reactive oxygen species (ROS) with antibacterial effectiveness are generated on copper surfaces mainly by the Fenton-type reaction.The antibacterial effectiveness is higher in Cu 2 O than in CuO.In this study we discussed the effects of the difference in the amount of generated ROS on the difference in the antibacterial effectiveness between Cu 2 O and CuO.Both Cu 2 O and CuO produced hydrogen peroxide (H 2 O 2 ) , hydroxyl radical (・OH) , and singlet oxygen ( 1 O 2 ) , but not superoxide radical (・O 2 -) .The concentration of H 2 O 2 produced was higher in Cu 2 O than in CuO.When catalase, a scavenger of H 2 O 2 , was added, the antibacterial activities of both Cu 2 O and CuO reduced to almost the same value.These experimental results indicate that Cu 2 O is higher in antibacterial effectiveness than CuO because Cu 2 O produced more H 2 O 2 than CuO.As ・OH was detected even when H 2 O 2 was scavenged by catalase before it reacted with Cu ion, a part of ・OH was generated by chemical reactions different from the Fenton-type reaction when copper oxides were in contact with water.Keywords ： copper oxides / antimicrobial activity / reactive oxygen species / hydrogen peroxide / hydroxyl radical / Contact Killing.
Source: Journal of Microorganism Control
DOI: 10.4265/jmc.30.1_19
Authors: YURIKA TANIGUCHI, HIROSHI KAWAKAMI, SADAO KOMEMUSHI, KEN HIROTA, TAKASHI OZAWA, KAZUNORI MIYAMOTO, HIROAKI NAKAYAMA, MASAHIKO WADA
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4408814755